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Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis is a relentless and devastating adult-onset neurodegenerative disease with no known cure. In mice with amyotrophic lateral sclerosis, CD4(+) T lymphocytes and wild-type microglia potentiate protective inflammatory responses and play a principal role in disease pathoprog...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3097891/ https://ncbi.nlm.nih.gov/pubmed/21596768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awr074 |
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