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Regulatory T Lymphocytes from ALS Mice Suppress Microglia and Effector T Lymphocytes Through Different Cytokine-Mediated Mechanisms

Activated microglia and infiltrating lymphocytes are neuropathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motoneuron disease. Although both cell types play pivotal roles in the ALS pathogenic process, the interactions between microglia and lymphocytes, specifically regulatory...

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Detalhes bibliográficos
Main Authors: Zhao, Weihua, Beers, David R., Liao, Bing, Henkel, Jenny S., Appel, Stanley H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897268/
https://ncbi.nlm.nih.gov/pubmed/22820142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.07.008
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