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Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
Neuroinflammation is a prominent pathological feature in the spinal cords of patients with amyotrophic lateral sclerosis (ALS), as well as in transgenic mouse models of inherited ALS, and is characterized by activated microglia. Earlier studies showed that activated microglia play important roles in...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126417/ https://ncbi.nlm.nih.gov/pubmed/22735487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.06.011 |
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