Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival

In amyotrophic lateral sclerosis (ALS) mice, regulatory T-lymphocytes (Tregs) are neuroprotective, slowing disease progression. To address whether Tregs and FoxP3, a transcription factor required for Treg function, similarly influence progression rates of ALS patients, T-lymphocytes from patients we...

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Detalhes bibliográficos
Main Authors: Henkel, Jenny S, Beers, David R, Wen, Shixiang, Rivera, Andreana L, Toennis, Karen M, Appel, Joan E, Zhao, Weihua, Moore, Dan H, Powell, Suzanne Z, Appel, Stanley H
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569654/
https://ncbi.nlm.nih.gov/pubmed/23143995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201544
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