Initial Testing (Stage 1) of the Anti-Microtubule Agents Cabazitaxel and Docetaxel, by the Pediatric Preclinical Testing Program

BACKGROUND: While microtubule destabilizing agents (principally vincristine) are in common use in pediatric oncology, the microtubule stabilizing taxanes are uncommonly used to treat childhood cancers. Cabazitaxel has been reported to have activity superior to that of docetaxel in preclinical models...

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Bibliographic Details
Published in:Pediatr Blood Cancer
Main Authors: Reynolds, C. Patrick, Kang, Min H., Maris, John M., Kolb, E. Anders, Gorlick, Richard, Wu, Jianrong, Kurmasheva, Raushan T., Houghton, Peter J., Smith, Malcolm A.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758191/
https://ncbi.nlm.nih.gov/pubmed/26154614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25611
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