ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells

Imprinting Control Regions (ICRs) need to maintain their parental allele-specific DNA methylation during early embryogenesis despite genome-wide demethylation and subsequent de novo methylation. ZFP57 and KAP1 are both required for maintaining the repressive DNA methylation and H3-lysine-9-trimethyl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Anvar, Zahra, Cammisa, Marco, Riso, Vincenzo, Baglivo, Ilaria, Kukreja, Harpreet, Sparago, Angela, Girardot, Michael, Lad, Shraddha, De Feis, Italia, Cerrato, Flavia, Angelini, Claudia, Feil, Robert, Pedone, Paolo V., Grimaldi, Giovanna, Riccio, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Gene regulation, Chromatin and Epigenetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756812/
https://ncbi.nlm.nih.gov/pubmed/26481358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1059
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi