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Disrupting spinal noradrenergic activation delays recovery of acute incision induced hypersensitivity and increases spinal glial activation in the rat

Clinical studies suggest that descending inhibitory controls from the brainstem are important for speeding recovery from pain following surgery. We examined the effects of destroying spinally projecting noradrenergic neurons via intrathecally administered antibody to dopamine β-hydroxylase conjugate...

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Detalhes bibliográficos
Publicado no:J Pain
Main Authors: Arora, Vipin, Morado-Urbina, Carlos Eduardo, Aschenbrenner, Carol A., Hayashida, Ken-ichiro, Wang, FuZhou, Martin, Thomas J., Eisenach, James C., Peters, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756646/
https://ncbi.nlm.nih.gov/pubmed/26545342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2015.10.009
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