Physiological evidence for diversification of IFNα- and IFNβ-mediated response programs in different autoimmune diseases

BACKGROUND: Activation of the type I interferon (IFN) response program is described for several autoimmune diseases, including systemic lupus erythematosus (SLE), multiple sclerosis (MS), myositis (IIM) and rheumatoid arthritis (RA). While IFNα contributes to SLE pathology, IFNβ therapy is often ben...

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Опубликовано в: :Arthritis Res Ther
Главные авторы: de Jong, Tamarah D., Vosslamber, Saskia, Mantel, Elise, de Ridder, Sander, Wesseling, John G., van der Pouw Kraan, Tineke C. T. M., Leurs, Cyra, Hegen, Harald, Deisenhammer, Florian, Killestein, Joep, Lundberg, Ingrid E., Vencovsky, Jiri, Nurmohamed, Mike T., van Schaardenburg, Dirkjan, Bultink, Irene E. M., Voskuyl, Alexandre E., Pegtel, D. Michiel, van der Laken, Conny J., Bijlsma, Johannes W. J., Verweij, Cornelis L.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756531/
https://ncbi.nlm.nih.gov/pubmed/26882897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-0946-9
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