Pharmacogenomics of Interferon-ß Therapy in Multiple Sclerosis: Baseline IFN Signature Determines Pharmacological Differences between Patients

BACKGROUND: Multiple sclerosis (MS) is a heterogeneous disease. In order to understand the partial responsiveness to IFNß in Relapsing Remitting MS (RRMS) we studied the pharmacological effects of IFNß therapy. METHODOLOGY: Large scale gene expression profiling was performed on peripheral blood of 1...

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書誌詳細
主要な著者: van Baarsen, Lisa G. M., Vosslamber, Saskia, Tijssen, Marianne, Baggen, Josefien M. C., van der Voort, Laura F., Killestein, Joep, van der Pouw Kraan, Tineke C. T. M., Polman, Chris H., Verweij, Cornelis L.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271130/
https://ncbi.nlm.nih.gov/pubmed/18382694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001927
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