Effect of prednisone on type I interferon signature in rheumatoid arthritis: consequences for response prediction to rituximab

INTRODUCTION: Elevated type I interferon (IFN) response gene (IRG) expression has proven clinical relevance in predicting rituximab non-response in rheumatoid arthritis (RA). Interference between glucocorticoids (GCs) and type I IFN signaling has been demonstrated in vitro. Since GC use and dose are...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: de Jong, Tamarah D, Vosslamber, Saskia, Blits, Marjolein, Wolbink, Gertjan, Nurmohamed, Mike T, van der Laken, Conny J, Jansen, Gerrit, Voskuyl, Alexandre E, Verweij, Cornelis L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416246/
https://ncbi.nlm.nih.gov/pubmed/25889713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0564-y
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