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Knocking down disease: a progress report on siRNA therapeutics
Small interfering RNAs (siRNAs), which downregulate gene expression guided by sequence complementarity, can be used therapeutically to block the synthesis of disease-causing proteins. The main obstacle to siRNA drugs — their delivery into the target cell cytosol — has been overcome to allow suppress...
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| Publicado no: | Nat Rev Genet |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4756474/ https://ncbi.nlm.nih.gov/pubmed/26281785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3978 |
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