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Interfering with disease: a progress report on siRNA-based therapeutics

RNA interference (RNAi) quietly crept into biological research in the 1990s when unexpected gene-silencing phenomena in plants and flatworms first perplexed scientists. Following the demonstration of RNAi in mammalian cells in 2001, it was quickly realized that this highly specific mechanism of sequ...

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Detalles Bibliográficos
Publicado en:Nat Rev Drug Discov
Main Authors: de Fougerolles, Antonin, Vornlocher, Hans-Peter, Maraganore, John, Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098199/
https://ncbi.nlm.nih.gov/pubmed/17541417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2310
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