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Interfering with disease: a progress report on siRNA-based therapeutics
RNA interference (RNAi) quietly crept into biological research in the 1990s when unexpected gene-silencing phenomena in plants and flatworms first perplexed scientists. Following the demonstration of RNAi in mammalian cells in 2001, it was quickly realized that this highly specific mechanism of sequ...
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| Veröffentlicht in: | Nat Rev Drug Discov |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7098199/ https://ncbi.nlm.nih.gov/pubmed/17541417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd2310 |
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