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Can roflumilast, a phosphodiesterase-4 inhibitor, improve clinical outcomes in patients with moderate-to-severe chronic obstructive pulmonary disease? A meta-analysis

BACKGROUND: Effects of roflumilast on lung function, symptoms, acute exacerbation and adverse events in patients with chronic obstructive pulmonary disease (COPD) are controversial. We aimed to further clarify the efficacy and safety of roflumilast in treatment of moderate-to-severe COPD. METHODS: F...

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Pubblicato in:Respir Res
Autori principali: Luo, Jian, Wang, Ke, Liu, Dan, Liang, Bin-Miao, Liu, Chun-Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756424/
https://ncbi.nlm.nih.gov/pubmed/26887407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0330-y
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