Can roflumilast, a phosphodiesterase-4 inhibitor, improve clinical outcomes in patients with moderate-to-severe chronic obstructive pulmonary disease? A meta-analysis

BACKGROUND: Effects of roflumilast on lung function, symptoms, acute exacerbation and adverse events in patients with chronic obstructive pulmonary disease (COPD) are controversial. We aimed to further clarify the efficacy and safety of roflumilast in treatment of moderate-to-severe COPD. METHODS: F...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Luo, Jian, Wang, Ke, Liu, Dan, Liang, Bin-Miao, Liu, Chun-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756424/
https://ncbi.nlm.nih.gov/pubmed/26887407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0330-y
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