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Can roflumilast, a phosphodiesterase-4 inhibitor, improve clinical outcomes in patients with moderate-to-severe chronic obstructive pulmonary disease? A meta-analysis

BACKGROUND: Effects of roflumilast on lung function, symptoms, acute exacerbation and adverse events in patients with chronic obstructive pulmonary disease (COPD) are controversial. We aimed to further clarify the efficacy and safety of roflumilast in treatment of moderate-to-severe COPD. METHODS: F...

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Bibliografiska uppgifter
I publikationen:Respir Res
Huvudupphovsmän: Luo, Jian, Wang, Ke, Liu, Dan, Liang, Bin-Miao, Liu, Chun-Tao
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756424/
https://ncbi.nlm.nih.gov/pubmed/26887407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0330-y
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