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Roflumilast and dyspnea in patients with moderate to very severe chronic obstructive pulmonary disease: a pooled analysis of four clinical trials

PURPOSE: Breathlessness is a predominant symptom of chronic obstructive pulmonary disease (COPD), making it a valuable outcome in addition to lung function to assess treatment benefit. The phosphodiesterase-4 inhibitor roflumilast has been shown to provide small but significant improvements in dyspn...

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Detalhes bibliográficos
Main Authors: Rennard, Stephen I, Sun, Shawn X, Tourkodimitris, Stavros, Rowe, Paul, Goehring, Udo M, Bredenbröker, Dirk, Calverley, Peter M A
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075954/
https://ncbi.nlm.nih.gov/pubmed/25018629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S55738
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