載入...

Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice

Altered function of the Gq-coupled, Group 1 metabotropic glutamate receptors, specifically mGlu5, is implicated in multiple mouse models of autism and intellectual disability. mGlu5 dysfunction has been most well characterized in the fragile X syndrome mouse model, the Fmr1 knock-out (KO) mouse, whe...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Neurosci
Main Authors: Guo, Weirui, Molinaro, Gemma, Collins, Katie A., Hays, Seth A., Paylor, Richard, Worley, Paul F., Szumlinski, Karen K., Huber, Kimberly M.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2016
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756152/
https://ncbi.nlm.nih.gov/pubmed/26888925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2921-15.2016
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!