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Homer1a-Dependent Crosstalk Between NMDA and Metabotropic Glutamate Receptors in Mouse Neurons

BACKGROUND: A large number of evidences suggest that group-I metabotropic glutamate receptors (mGluR1a, 1b, 1c, 5a, 5b) can modulate NMDA receptor activity. Interestingly, a physical link exists between these receptors through a Homer-Shank multi-protein scaffold that can be disrupted by the immedia...

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Detalhes bibliográficos
Main Authors: Bertaso, Federica, Roussignol, Gautier, Worley, Paul, Bockaert, Joël, Fagni, Laurent, Ango, Fabrice
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841198/
https://ncbi.nlm.nih.gov/pubmed/20305784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009755
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