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Activation of Peripheral Mu-Opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) amide Leads to Modality-preferred Inhibition of Neuropathic Pain

BACKGROUND: Opioids have long been regarded as the most effective drugs for treatment of severe acute and chronic pain. Unfortunately, their therapeutic efficacy and clinical utility has been limited because of central and peripheral side effects. METHODS: To determine the therapeutic value of perip...

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書誌詳細
出版年:Anesthesiology
主要な著者: Tiwari, Vinod, Yang, Fei, He, Shao-Qiu, Shechter, Ronen, Zhang, Chen, Shu, Bin, Zhang, Tong, Tiwari, Vineeta, Wang, Yun, Dong, Xinzhong, Guan, Yun, Raja, Srinivasa N.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755859/
https://ncbi.nlm.nih.gov/pubmed/26756519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0000000000000993
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