Claudin-2-dependent paracellular channels are dynamically gated

Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured. We report a novel trans-tight junction patch clamp tec...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Weber, Christopher R, Liang, Guo Hua, Wang, Yitang, Das, Sudipto, Shen, Le, Yu, Alan S L, Nelson, Deborah J, Turner, Jerrold R
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Biophysics and Structural Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755754/
https://ncbi.nlm.nih.gov/pubmed/26568313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09906
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