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Claudin-4 forms paracellular chloride channel in the kidney and requires claudin-8 for tight junction localization

Tight junctions (TJs) play a key role in mediating paracellular ion reabsorption in the kidney. The paracellular pathway in the collecting duct of the kidney is a predominant route for transepithelial chloride reabsorption that determines the extracellular NaCl content and the blood pressure. Howeve...

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Autors principals: Hou, Jianghui, Renigunta, Aparna, Yang, Jing, Waldegger, Siegfried
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964195/
https://ncbi.nlm.nih.gov/pubmed/20921420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009399107
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