Claudin-16 and claudin-19 interact and form a cation-selective tight junction complex

Tight junctions (TJs) play a key role in mediating paracellular ion reabsorption in the kidney. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is an inherited disorder caused by mutations in the genes encoding the TJ proteins claudin-16 (CLDN16) and CLDN19; however, the mec...

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Bibliografski detalji
Glavni autori: Hou, Jianghui, Renigunta, Aparna, Konrad, Martin, Gomes, Antonio S., Schneeberger, Eveline E., Paul, David L., Waldegger, Siegfried, Goodenough, Daniel A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2008
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2176193/
https://ncbi.nlm.nih.gov/pubmed/18188451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33970
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