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Claudin-1 and claudin-2 expression are elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal adenocarcinoma. The factors that result in IBD-associated carcinogenesis are not understood. We hypothesized that altered expression of intestinal epithelial tight junction proteins might contribute to neop...

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Detalhes bibliográficos
Main Authors: Weber, Christopher R., Nalle, Sam C., Tretiakova, Maria, Rubin, David T., Turner, Jerrold R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586671/
https://ncbi.nlm.nih.gov/pubmed/18711353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.78
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