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Claudin-1 and claudin-2 expression are elevated in inflammatory bowel disease and may contribute to early neoplastic transformation

Patients with inflammatory bowel disease (IBD) are at increased risk of developing colorectal adenocarcinoma. The factors that result in IBD-associated carcinogenesis are not understood. We hypothesized that altered expression of intestinal epithelial tight junction proteins might contribute to neop...

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Bibliografiske detaljer
Main Authors: Weber, Christopher R., Nalle, Sam C., Tretiakova, Maria, Rubin, David T., Turner, Jerrold R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586671/
https://ncbi.nlm.nih.gov/pubmed/18711353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2008.78
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