Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin

The plant secondary metabolite and common food additive dihydrocoumarin (DHC) is an inhibitor of the Sirtuin family of NAD(+)-dependent deacetylases. Sirtuins are key regulators of epigenetic processes that maintain silent chromatin in yeast and have been linked to gene expression, metabolism, apopt...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Jacobi, Jennifer L., Yang, Bo, Li, Xu, Menze, Anna K., Laurentz, Sara M., Janle, Elsa M., Ferruzzi, Mario G., McCabe, George P., Chapple, Clint, Kirchmaier, Ann L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755582/
https://ncbi.nlm.nih.gov/pubmed/26882112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149207
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