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Impacts on Sirtuin Function and Bioavailability of the Dietary Bioactive Compound Dihydrocoumarin
The plant secondary metabolite and common food additive dihydrocoumarin (DHC) is an inhibitor of the Sirtuin family of NAD(+)-dependent deacetylases. Sirtuins are key regulators of epigenetic processes that maintain silent chromatin in yeast and have been linked to gene expression, metabolism, apopt...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755582/ https://ncbi.nlm.nih.gov/pubmed/26882112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149207 |
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