Biliatresone, a Reactive Natural Toxin from Dysphania glomulifera and D. littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone

We identified a reactive natural toxin, biliatresone, from Dysphania glomulifera and D. littoralis collected in Australia that produces extrahepatic biliary atresia in a zebrafish model. Three additional isoflavonoids, including the known isoflavone betavulgarin, were also isolated. Biliatresone is...

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Veröffentlicht in:Chem Res Toxicol
Hauptverfasser: Koo, Kyung A., Lorent, Kristin, Gong, Weilong, Windsor, Peter, Whittaker, Stephen J., Pack, Michael, Wells, Rebecca G., Porter, John R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755499/
https://ncbi.nlm.nih.gov/pubmed/26175131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.5b00227
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