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1,3-Diaryl-2-propenones and 2-Benzylidene-1,3-indandiones: A Quest for Compounds Displaying Greater Toxicity to Neoplasms than Normal Cells

A series of 1,3-diaryl-2-propenones 2a–j and analogous 2-benzylidene-1,3-indandiones 3a–j were evaluated against various neoplasms and normal cells. In general, greater cytotoxic potencies and selective toxicity to human malignant cells were observed by the compounds in series 2 rather than 3. In pa...

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Bibliografske podrobnosti
Main Authors: Pati, Hari N., Das, Umashankar, Sakagami, Hiroshi, Kawase, Masame, Chu, Qing, Wang, Qintao, Stables, James P., Dimmock, Jonathan R.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327711/
https://ncbi.nlm.nih.gov/pubmed/20806272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ardp.200900308
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