Elevated Tonic Extracellular Dopamine Concentration and Altered Dopamine Modulation of Synaptic Activity Precede Dopamine Loss in the Striatum of Mice Overexpressing Human α-Synuclein

Overexpression or mutation of α-synuclein (α-Syn), a protein associated with presynaptic vesicles, causes familial forms of Parkinson’s disease in humans and is also associated with sporadic forms of the disease. We used in vivo microdialysis, tissue content analysis, behavioral assessment, and whol...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neurosci Res
Autors principals: Lam, Hoa A., Wu, Nanping, Cely, Ingrid, Kelly, Rachel L., Hean, Sindalana, Richter, Franziska, Magen, Iddo, Cepeda, Carlos, Ackerson, Larry C., Walwyn, Wendy, Masliah, Eliezer, Chesselet, Marie-Françoise, Levine, Michael S., Maidment, Nigel T.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755488/
https://ncbi.nlm.nih.gov/pubmed/21488084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22611
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars