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Elevated Tonic Extracellular Dopamine Concentration and Altered Dopamine Modulation of Synaptic Activity Precede Dopamine Loss in the Striatum of Mice Overexpressing Human α-Synuclein

Overexpression or mutation of α-synuclein (α-Syn), a protein associated with presynaptic vesicles, causes familial forms of Parkinson’s disease in humans and is also associated with sporadic forms of the disease. We used in vivo microdialysis, tissue content analysis, behavioral assessment, and whol...

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Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci Res
Egile Nagusiak: Lam, Hoa A., Wu, Nanping, Cely, Ingrid, Kelly, Rachel L., Hean, Sindalana, Richter, Franziska, Magen, Iddo, Cepeda, Carlos, Ackerson, Larry C., Walwyn, Wendy, Masliah, Eliezer, Chesselet, Marie-Françoise, Levine, Michael S., Maidment, Nigel T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755488/
https://ncbi.nlm.nih.gov/pubmed/21488084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22611
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