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Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding

Hexameric helicases control both the initiation and the elongation phase of DNA replication. The toroidal structure of these enzymes provides an inherent challenge in the opening and loading onto DNA at origins, as well as the conformational changes required to exclude one strand from the central ch...

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Detalhes bibliográficos
Publicado no:F1000Res
Autor principal: Trakselis, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755419/
https://ncbi.nlm.nih.gov/pubmed/26918187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7509.1
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