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Structural Mechanisms of Hexameric Helicase Loading, Assembly, and Unwinding

Hexameric helicases control both the initiation and the elongation phase of DNA replication. The toroidal structure of these enzymes provides an inherent challenge in the opening and loading onto DNA at origins, as well as the conformational changes required to exclude one strand from the central ch...

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Detaylı Bibliyografya
Yayımlandı:F1000Res
Yazar: Trakselis, Michael A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: F1000Research 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755419/
https://ncbi.nlm.nih.gov/pubmed/26918187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.7509.1
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