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Impaired striatal function in Huntington's disease is due to aberrant p75NTR signaling
Huntington's disease (HD) is a rare genetic neurodegenerative disorder for which there is currently no cure. Early hyperkinetic motor symptoms are consistent with reduced activity of indirect pathway striatal projection neurons (iSPNs) responsible for suppression of unwanted actions. Our recent...
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| Veröffentlicht in: | Rare Dis |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4755240/ https://ncbi.nlm.nih.gov/pubmed/26942104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/2167549X.2014.968482 |
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