Neurotrophin receptor p75(NTR) mediates Huntington’s disease–associated synaptic and memory dysfunction

Learning and memory deficits are early clinical manifestations of Huntington’s disease (HD). These cognitive impairments have been mainly associated with frontostriatal HD pathology; however, compelling evidence provided by several HD murine models suggests that the hippocampus may contribute to syn...

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Bibliografiske detaljer
Main Authors: Brito, Verónica, Giralt, Albert, Enriquez-Barreto, Lilian, Puigdellívol, Mar, Suelves, Nuria, Zamora-Moratalla, Alfonsa, Ballesteros, Jesús J., Martín, Eduardo D., Dominguez-Iturza, Nuria, Morales, Miguel, Alberch, Jordi, Ginés, Sílvia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191006/
https://ncbi.nlm.nih.gov/pubmed/25180603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74809
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