Neurotrophin receptor p75(NTR) mediates Huntington’s disease–associated synaptic and memory dysfunction

Learning and memory deficits are early clinical manifestations of Huntington’s disease (HD). These cognitive impairments have been mainly associated with frontostriatal HD pathology; however, compelling evidence provided by several HD murine models suggests that the hippocampus may contribute to syn...

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Main Authors: Brito, Verónica, Giralt, Albert, Enriquez-Barreto, Lilian, Puigdellívol, Mar, Suelves, Nuria, Zamora-Moratalla, Alfonsa, Ballesteros, Jesús J., Martín, Eduardo D., Dominguez-Iturza, Nuria, Morales, Miguel, Alberch, Jordi, Ginés, Sílvia
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4191006/
https://ncbi.nlm.nih.gov/pubmed/25180603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74809
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