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Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies

Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain suggesting that besides a decrease on BDNF...

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Bibliografische gegevens
Hoofdauteurs: Brito, V, Puigdellívol, M, Giralt, A, del Toro, D, Alberch, J, Ginés, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641339/
https://ncbi.nlm.nih.gov/pubmed/23598407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.116
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