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Imbalance of p75(NTR)/TrkB protein expression in Huntington's disease: implication for neuroprotective therapies

Neuroprotective therapies based on brain-derived neurotrophic factor (BDNF) administration have been proposed for Huntington's disease (HD) treatment. However, our group has recently reported reduced levels of TrkB in HD mouse models and HD human brain suggesting that besides a decrease on BDNF...

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Detalhes bibliográficos
Main Authors: Brito, V, Puigdellívol, M, Giralt, A, del Toro, D, Alberch, J, Ginés, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641339/
https://ncbi.nlm.nih.gov/pubmed/23598407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.116
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