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Engineered hapten‐binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery

Hapten‐binding antibodies have for more than 50 years played a pivotal role in immunology, paving the way to antibody generation (as haptens are very important and robust immunogens), to antibody characterization (as the first structures generated more than 40 years ago were those of hapten binders)...

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Podrobná bibliografie
Vydáno v:Immunol Rev
Hlavní autoři: Dengl, Stefan, Sustmann, Claudio, Brinkmann, Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755198/
https://ncbi.nlm.nih.gov/pubmed/26864111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12386
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