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Engineered hapten‐binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery

Hapten‐binding antibodies have for more than 50 years played a pivotal role in immunology, paving the way to antibody generation (as haptens are very important and robust immunogens), to antibody characterization (as the first structures generated more than 40 years ago were those of hapten binders)...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Dengl, Stefan, Sustmann, Claudio, Brinkmann, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755198/
https://ncbi.nlm.nih.gov/pubmed/26864111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12386
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