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Engineered hapten‐binding antibody derivatives for modulation of pharmacokinetic properties of small molecules and targeted payload delivery

Hapten‐binding antibodies have for more than 50 years played a pivotal role in immunology, paving the way to antibody generation (as haptens are very important and robust immunogens), to antibody characterization (as the first structures generated more than 40 years ago were those of hapten binders)...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Immunol Rev
Main Authors: Dengl, Stefan, Sustmann, Claudio, Brinkmann, Ulrich
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755198/
https://ncbi.nlm.nih.gov/pubmed/26864111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12386
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