Increased risk of volume overload with plasma compared with four‐factor prothrombin complex concentrate for urgent vitamin K antagonist reversal

Eitemau Tebyg

• Safety of a Four‐factor Prothrombin Complex Concentrate Versus Plasma for Vitamin K Antagonist Reversal: An Integrated Analysis of Two Phase IIIb Clinical Trials
  gan: Milling, Truman J., et al.
  Cyhoeddwyd: (2016)
• Efficacy and Safety of a 4-Factor Prothrombin Complex Concentrate in Patients on Vitamin K Antagonists Presenting With Major Bleeding A Randomized, Plasma-Controlled, Phase IIIb Study
  gan: Sarode, Ravi, et al.
  Cyhoeddwyd: (2013)
• Four-factor prothrombin complex concentrate versus plasma for rapid vitamin K antagonist reversal in patients needing urgent surgical or invasive interventions: a phase 3b, open-label, non-inferiority, randomised trial
  gan: Goldstein, Joshua N, et al.
  Cyhoeddwyd: (2015)
• Thromboembolic Events After Vitamin K Antagonist Reversal With 4-Factor Prothrombin Complex Concentrate: Exploratory Analyses of Two Randomized, Plasma-Controlled Studies
  gan: Milling, Truman J., et al.
  Cyhoeddwyd: (2015)
• Prothrombin complex concentrates for perioperative vitamin K antagonist and non vitamin K anticoagulant reversal
  gan: Levy, Jerrold H, et al.
  Cyhoeddwyd: (2018)