Safety of a Four‐factor Prothrombin Complex Concentrate Versus Plasma for Vitamin K Antagonist Reversal: An Integrated Analysis of Two Phase IIIb Clinical Trials

OBJECTIVES: Clinicians often need to rapidly reverse vitamin K antagonists (VKAs) in the setting of major hemorrhage or urgent need for surgery. Little is known about the safety profile of the traditional reversal agent, plasma, or the newly approved agent, four‐factor prothrombin complex concentrat...

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Bibliografische gegevens
Gepubliceerd in:Acad Emerg Med
Hoofdauteurs: Milling, Truman J., Refaai, Majed A., Sarode, Ravi, Lewis, Brandon, Mangione, Antoinette, Durn, Billie L., Harman, Amy, Lee, Martin L., Goldstein, Joshua N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Original Contributions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071715/
https://ncbi.nlm.nih.gov/pubmed/26822172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acem.12911
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