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Host Anti-antibody Responses Following Adeno-associated Virus–mediated Delivery of Antibodies Against HIV and SIV in Rhesus Monkeys

Long-term delivery of antibodies against the human immunodeficiency virus (HIV) using adeno-associated virus (AAV) vectors is a promising approach for the prevention or treatment of HIV infection. However, host antibody responses to the delivered antibody are a serious concern that could significant...

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Détails bibliographiques
Publié dans:Mol Ther
Auteurs principaux: Martinez-Navio, José M, Fuchs, Sebastian P, Pedreño-López, Sònia, Rakasz, Eva G, Gao, Guangping, Desrosiers, Ronald C
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754551/
https://ncbi.nlm.nih.gov/pubmed/26444083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2015.191
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