Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

Genetic studies have revealed significant overlaps of risk genes among psychiatric disorders. However, it is not clear how different mutations of the same gene contribute to different disorders. We characterized two lines of mutant mice with Shank3 mutations linked to ASD and schizophrenia. We found...

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Gepubliceerd in:Neuron
Hoofdauteurs: Zhou, Yang, Kaiser, Tobias, Monteiro, Patrícia, Zhang, Xiangyu, Van der Goes, Marie. S., Wang, Dongqing, Barak, Boaz, Zeng, Menglong, Li, Chenchen, Lu, Congyi, Wells, Michael, Amaya, Aldo, Nguyen, Shannon, Lewis, Michael, Sanjana, Neville, Zhou, Yongdi, Zhang, Mingjie, Zhang, Feng, Fu, Zhanyan, Feng, Guoping
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4754122/
https://ncbi.nlm.nih.gov/pubmed/26687841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.023
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