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Androgen Deprivation Induces Senescence Characteristics in Prostate Cancer Cells In vitro and In vivo

BACKGROUND: The treatment of non-localized prostate cancer involves androgen deprivation (AD) therapy which results in tumor regression. Apoptosis has been implicated in the tumor response to AD, but constitutes a small fraction of the total tumor at any time. Cellular senescence is a response to su...

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Bibliografische gegevens
Gepubliceerd in:Prostate
Hoofdauteurs: Ewald, Jonathan A., Desotelle, Joshua A., Church, Dawn R., Yang, Bing, Huang, Wei, Laurila, Timo A., Jarrard, David F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753826/
https://ncbi.nlm.nih.gov/pubmed/22911222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22571
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