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Therapy-Induced Senescence in Cancer

Cellular senescence is a response to nonlethal stress that results in persistent cytostasis with a distinct morphological and biochemical phenotype. The senescence phenotype, detected in tumors through the expression of mRNA and protein markers, can be generated in cancer cells lacking functional p5...

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Autori principali: Ewald, Jonathan A., Desotelle, Joshua A., Wilding, George, Jarrard, David F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957429/
https://ncbi.nlm.nih.gov/pubmed/20858887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq364
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