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Regulation of lipid synthesis by the RNA helicase Mov10 controls Wnt5a production

Expression of the Wnt ligand Wnt5a is frequently elevated in melanoma and is thought to be a critical regulator of cell movement during metastasis. However, the mechanisms regulating its expression are unknown. We find that the level of secreted Wnt5a varies by as much as 10-fold between cell lines...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Wang, W, Snyder, N, Worth, A J, Blair, I A, Witze, E S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753523/
https://ncbi.nlm.nih.gov/pubmed/26029828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2015.15
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