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Role for the MOV10 RNA helicase in Polycomb-mediated repression of the INK4a tumor suppressor

Several lines of evidence point to a role for non-coding RNA in transcriptional repression by Polycomb group (PcG) proteins but the precise mechanism remains unclear. Here we show that MOV10, a putative RNA helicase previously implicated in post-transcriptional gene silencing, co-purifies and intera...

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Detalhes bibliográficos
Main Authors: El Messaoudi-Aubert, Selma, Nicholls, James, Maertens, Goedele N., Brookes, Sharon, Bernstein, Emily, Peters, Gordon
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929459/
https://ncbi.nlm.nih.gov/pubmed/20543829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1824
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