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MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells

MOV10 protein, a putative RNA helicase and component of the RNA–induced silencing complex (RISC), inhibits retrovirus replication. We show that MOV10 also severely restricts human LINE1 (L1), Alu, and SVA retrotransposons. MOV10 associates with the L1 ribonucleoprotein particle, along with other RNA...

詳細記述

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書誌詳細
主要な著者: Goodier, John L., Cheung, Ling E., Kazazian, Haig H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475670/
https://ncbi.nlm.nih.gov/pubmed/23093941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002941
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