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Extreme dNTP Pool Changes and Hypermutability in dcd ndk Strains
Cells lacking deoxycytidine deaminase (DCD) have been shown to have imbalances in the normal dNTP pools that lead to multiple phenotypes, including increased mutagenesis, increased sensitivity to oxidizing agents, and to a number of antibiotics. In particular, there is an increased dCTP pool, often...
Shranjeno v:
| izdano v: | Mutat Res |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753124/ https://ncbi.nlm.nih.gov/pubmed/26789486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mrfmmm.2015.12.004 |
| Oznake: |
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