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Radical-mediated ring contraction in the biosynthesis of 7-deazapurines
Pyrrolopyrimidine containing natural products are widely distributed in Nature. The biosynthesis of the 7-deazapurine moiety that is common to all pyrrolopyrimidines entails multiple steps, one of which is a complex radical-mediated ring contraction reaction catalyzed by CDG synthase. Herein we revi...
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| Veröffentlicht in: | Curr Opin Struct Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4753066/ https://ncbi.nlm.nih.gov/pubmed/26643180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.11.005 |
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