Estradiol regulates human QT-interval: acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking

BACKGROUND: Modulation of cardiac repolarization by sexual hormones is controversial and hormonal effects on ion channels remain largely unknown. In the present translational study, we therefore assessed the relationship between QTc duration and gonadal hormones and studied underlying mechanisms. ME...

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Dades bibliogràfiques
Publicat a:Eur Heart J
Autors principals: Anneken, Lars, Baumann, Stefan, Vigneault, Patrick, Biliczki, Peter, Friedrich, Corinna, Xiao, Ling, Girmatsion, Zenawit, Takac, Ina, Brandes, Ralf P., Kissler, Stefan, Wiegratz, Inka, Zumhagen, Sven, Stallmeyer, Birgit, Hohnloser, Stefan H., Klingenheben, Thomas, Schulze-Bahr, Eric, Nattel, Stanley, Ehrlich, Joachim R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Basic Science
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4753025/
https://ncbi.nlm.nih.gov/pubmed/26271031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehv371
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